When a VDB with same name and version is re-deployed, the new re-deployed VDB may have its metadata changed. In this case if Teiid has any

PreparedPlanCache
ResultSetCache

they need to flushed for that VDB, otherwise it will produce wrong results. One issue is there could be active connections on VDB, those need to be terminated also. Based on how failover is configured they may re-connect on the next query automatically.