Add the following code to your endpoint implementation to sleep while waiting for the service endpoint to be ready to process the message: - @Override protected SOAPMessage processSOAPMessage(String fromName, InputStream reqMessage) throws SOAPException, IOException, RemoteException { ServiceEndpointManagerFactory factory = ServiceEndpointManagerFactory.getInstance(); ServiceEndpointManager epManager = factory.getServiceEndpointManager(); ObjectName sepID = getServiceEndpointForDestination(epManager, fromName); ServiceEndpoint sep = epManager.getServiceEndpointByID(sepID); long startTime = System.currentTimeMillis(); State state = sep.getState(); log.info("State=" + state); while (state != State.STARTED && (System.currentTimeMillis() - startTime < 60000)) { try { Thread.sleep(1000); state = sep.getState(); log.info("State=" + state); } catch (InterruptedException e) { throw new EJBException(e); } } return super.processSOAPMessage(fromName, reqMessage); } private ObjectName getServiceEndpointForDestination(ServiceEndpointManager epManager, String fromName) { ObjectName sepID = null; for (ObjectName aux : epManager.getServiceEndpoints()) { String jmsProp = aux.getKeyProperty("jms"); if (jmsProp != null && jmsProp.equals(fromName)) { sepID = aux; break; } } return sepID; }